Nuclear medicine imaging is a diagnostic technique that uses radioactive materials, known as radiopharmaceuticals, to visualize various functions and processes within the body. This type of imaging is used to diagnose and monitor various conditions, including cancer, heart disease and neurological disorders. Nuclear medicine imaging works by injecting or ingesting a small amount of radioactive material into the patient's body. The radiopharmaceuticals are designed to bind to specific organs or tissues, depending on the condition being studied. Once the radiopharmaceutical is in place, it emits radiation, which can be detected by a special camera called a gamma camera. For the management of patients with gastro-entero-pancreatic neuroendocrine tumors, nuclear medicine imaging is a powerful diagnostic tool that was primarily developed with some cellular characteristics that are unique to the neuroendocrine phenotype in mind. As a result, the development of diagnostic radiotracers has been thought to involve the overexpression of particular trans membrane receptors as well as the capacity of cells to absorb, accumulate and decarboxylate amine precursors. For radionuclide imaging of neuroendocrine tumors, the glycolytic metabolism, which is not a specific energetic pathway, has also been proposed.