Prevalence of Isolated Proteinuria in Students of University of Maiduguria, Borno State Nigeria: An Early Indicator of Renal Insufficiency

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Proteinuria as deÙ½ned by Michael  is the excretion of urinary protein of greater than 150mg per day. In healthy person urinary protein excretion varies considerably and may reach proteinuric levels under several conditions. About 20% of the normally excreted proteins is low molecular weight type such as immunoglobulin (M.Wt about 20 KDa), 40% albumin (M.Wt=65 KDa) and 40% is made up of TammHorsfall mucoproteins secreted by the distal tubule . An isolated proteinuria is deÙ½ned as excretion of urinary protein of less than 2 g per day in an individual with normal renal function test, no evidence of systemic diseases with renal complication, normal urinary sediment, and normal blood pressure. НLs is usually discovered incidentally in routine dipstick urinalysis . However, current scLentLÙ½c evidence shows that 20%of such individual will develop renal LnsuÙ¹cLenc\ DÑ–er 10 years of follow-up and therefore should be monitored by blood pressure measurement, urinalysis and serum creatinine DÑ–er every six months . Isolated proteinuria of more than 2 g per day is rare and usually sLgnLÙ½es glomerular disease.