Histopathology involves the microscopic examination of tissue samples to identify any abnormal cellular changes that may indicate a specific disease or condition. In the context of dyspepsia, histopathology can help diagnose underlying conditions such as peptic ulcer disease, gastritis, or Helicobacter pylori (H. pylori) infection. The findings of endoscopy and histopathology among patients with dyspepsia vary depending on the underlying cause of their symptoms. For example, if a patient has an ulcer, endoscopy may reveal a visible erosion or hole in the lining of the stomach or duodenum. Histopathology can confirm the presence of an ulcer and identify any associated inflammation or infection. Similarly, if a patient has gastritis, endoscopy may reveal redness or inflammation in the lining of the stomach. Histopathology can confirm the diagnosis and identify any specific inflammatory changes that may be present. In cases where the cause of dyspepsia is not immediately apparent, endoscopy and histopathology can help rule out certain conditions and guide further diagnostic testing or treatment. For example, if endoscopy and histopathology do not reveal any abnormalities, the patient may undergo additional testing such as imaging studies or blood tests to further evaluate their symptoms.